OPENING THE TOOLKIT
Evidence to read.
Systems to use.
Publications, genomes, experimental tools and visual resources for exploring the unicellular ancestry of animals.
Open the resources↓THE RESOURCE MAP
From an idea
to a reusable system.
Explore evolutionary distribution of key animal genes.
OPEN ↗02 · LIVING SYSTEMSOrganisms:Cultures and Genomes
Life cycles, experimental questions, available genomes and model-system histories.
OPEN ↗03 · METHODSMethodsGenetic tools, protocols and experimental systems for comparative cell biology.
EXPLORE ↗04 · DISCOVERYMissinglineages
The known unknowns around animals and the path from environmental DNA to culture.
OPEN ↗05 · PERSPECTIVESIdeasConceptual frameworks, alternative routes and open debates about animal origins.
READ ↗06 · WATCHMovies &explainers
Live microscopy, research stories and visual explanations from the laboratory.
WATCH ↗07 · CONNECTScience &society
Outreach, education, mentoring, inclusion and the laboratory’s public life.
EXPLORE ↗SELECTED PUBLICATIONS
The papers behind
the platform.
A curated route through the work most closely connected to animal origins, emerging model systems and the evolution of the animal toolkit.
selected papers
in view
A unicellular relative links aggregative multicellularity to animal origins
Ministeria vibransNature
Beyond Diffusion: Bayesian Learning Strategies in Single-Cell Life
Capsaspora owczarzakiPRX Life
A smartphone analogy to explore the origin of animals
Conceptual perspectiveThe EMBO Journal
Animals have expanded the evolutionary legacy of unicellular ancestors in blood cells
Holozoa · MetazoaPNAS
CRISPR-Cas9 genome editing in Corallochytrium limacisporum
Corallochytrium limacisporumOpen Biology
Ichthyosporea: a window into the origin of animals
IchthyosporeaCommunications Biology
Chemical factors induce aggregative multicellularity in a close unicellular relative of animals
Capsaspora owczarzakiPNAS
The origin of metazoan multicellularity: a potential microbial black swan event
Conceptual perspectiveAnnual Review of Microbiology
Divergent genomic trajectories predate the origin of animals and fungi
OpisthokontaNature
Stable transfection in protist Corallochytrium limacisporum identifies novel cellular features
Corallochytrium limacisporumCurrent Biology
Genetic tool development in marine protists: emerging model organisms for experimental cell biology
Emerging protist modelsNature Methods
Integrin-mediated adhesion in the unicellular holozoan Capsaspora owczarzaki
Capsaspora owczarzakiCurrent Biology
A unicellular relative of animals generates a layer of polarized cells by actomyosin-dependent cellularization
Sphaeroforma arcticaeLife
Transfection of Capsaspora owczarzaki, a close unicellular relative of animals
Capsaspora owczarzakiDevelopment
Decoupling of nuclear division cycles and cell size during coenocytic growth
Sphaeroforma arcticaCurrent Biology
Dynamics of genomic innovation in the unicellular ancestry of animals
Unicellular HolozoaeLife
The dynamic regulatory genome of Capsaspora and the origin of animal multicellularity
Capsaspora owczarzakiCell
High-throughput proteomics reveals the unicellular roots of animal phosphosignaling and cell differentiation
Capsaspora owczarzakiDevelopmental Cell
Phylogenomics reveals convergent evolution of lifestyles in close relatives of animals and fungi
OpisthokontaCurrent Biology
Development of ichthyosporeans sheds light on the origin of metazoan multicellularity
Creolimax fragrantissimaDevelopmental Biology
Early evolution of the T-box transcription factor family
Capsaspora · XenopusPNAS
The Capsaspora genome reveals a complex unicellular prehistory of animals
Capsaspora owczarzakiNature Communications
Genomic survey of premetazoans shows deep conservation of cytoplasmic tyrosine kinases
Capsaspora · MinisteriaScience Signaling
For the complete publication list, see:
